by LabStorage | 0,April 4, 2022 | LabStore Highlights
In Part 1 of this series, we discussed the theory and science of wax infiltration in routine tissue processing. A key point stablished was that the basic paraffin molecule is a simple straight chain molecule composed of hydrogen and carbon atoms. However, for the...
by LabStorage | 0,March 1, 2022 | LabStore Highlights
Paraffin wax is used in the tissue processing sequence where, after fixation, dehydration, and clearing, the tissues are infiltrated with wax to give it structure and support during microtomy. There are a multitude of options for the user to consider, and oftentimes...
by LabStorage | 0,February 9, 2022 | LabStore Highlights
In Part 1 of this series on hard storage systems, we discussed low volume options for the original pathologic sample items (raw tissue, tissue blocks/tissue slides) upon which the diagnosis was made. And how, with the need for legal liability, there is a need for...
by LabStorage | 0,January 11, 2022 | LabStore Highlights
The discipline of Anatomic Pathology is understandably one of the greatest hoarders in the medical profession. While so many other fields of medicine have transitioned to electronic data retention for historical records, in anatomic pathology there still exists the...
by LabStorage | 0,December 1, 2021 | LabStore Highlights
In Part 1 of this series, we discussed enhanced methods to guard against specimen loss during tissue fixation and processing. In this second part, we will continue that discussion from the perspective of biopsy cassettes; those tissue containment devices designed...
by LabStorage | 0,November 1, 2021 | LabStore Highlights
In the world of Histopathology, seldom do we still see the need for large, hunk-like specimens surgically removed for patient diagnoses. In the mid-2000s the profession began to see a transition from sizeable specimens that would consume a considerable majority of a...
by LabStorage | 0,October 1, 2021 | LabStore Highlights
In the previous series titled, “Understanding H&E Staining”, it was stated that high volume H&E staining laboratories would experience some degree of moderate to significant loss of stain intensity during the course of their daily run. Therefore, these labs...
by LabStorage | 0,September 1, 2021 | LabStore Highlights
In this third and final piece of our series on H&E staining comprehension, we will discuss a) the steps involved in achieving the optimal stain; a concept known as balance of coloration; and b) quality assurance steps necessary to monitor and maintain consistency...
by LabStorage | 0,August 1, 2021 | LabStore Highlights
In Part 1 of this article, we discussed the origin, general qualities, and staining mechanism of the basic dye, hematoxylin. In this feature, Part 2, we will discuss the most common and appropriate counterstain for routine histological staining, Eosin. Eosin, with its...
by LabStorage | 0,July 1, 2021 | LabStore Highlights
For centuries scientists and researchers have used tissue specific dyes to advance the knowledge and comprehension of cells and organs. After developing methods of preserving tissues, then performing thin layer sectioning, specimens then had to be stained in such a...
by LabStorage | 0,June 1, 2021 | LabStore Highlights
In Part 1 of this series on maintaining fixation, we discussed fixation from a histochemical perspective illustrating the process and molecular changes in tissues. Two key factors that were emphasized were the penetration rate of fixatives and the time needed for the...
by LabStorage | 0,May 1, 2021 | LabStore Highlights
The preservation and study of tissue and cells is dependent upon one’s ability to stop all cellular degradation and autolysis once tissues have been removed from the body. Cells must be suspended or ‘fixed’ to stop enzymatic breakdown and allow normal and abnormal...
